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        "journal": "Example Orthopaedic Journal",
        "doi": "10.0000/example.tha-pji",
        "pmid": "00000001",
        "studyType": "Meta-analysis",
        "subspecialty": "Adult Reconstruction",
        "population": "Arthroplasty / PJI patients",
        "interventionExposure": "Revision / exchange strategy",
        "comparison": "待人工補讀",
        "outcomes": "Infection control, revision outcome, complications",
        "mainFindings": "PJI diagnosis needs combined clinical, serologic, synovial, and microbiologic evidence.；Revision strategy depends on organism, host, implant stability, and soft tissue condition.",
        "limitations": "研究異質性、納入研究品質與 publication bias 待評估",
        "futureDirections": "補讀全文後確認研究缺口、樣本數、bias 與可外推性。",
        "researchGap": "需要確認哪些 subgroup、outcome 或長期結果仍無一致證據。",
        "clinicalRelevance": "可能影響骨科臨床決策或教學重點。",
        "useInReview": "作為背景與證據總結的代表文獻。",
        "themeTags": [
          "clinical-outcomes",
          "mechanism-risk",
          "methods-evidence",
          "teaching-practice"
        ],
        "representativeScore": 10
      },
      {
        "rank": 2,
        "id": "fixture-osteoporosis-safety",
        "title": "Osteoporosis Drug Safety Update",
        "year": "2025",
        "journal": "Example Medical Journal",
        "doi": "10.0000/example.osteoporosis",
        "pmid": "00000002",
        "studyType": "Systematic review",
        "subspecialty": "Bone Metabolism",
        "population": "Arthroplasty / PJI patients",
        "interventionExposure": "Medication / prevention strategy",
        "comparison": "待人工補讀",
        "outcomes": "Fracture prevention, adverse events, safety",
        "mainFindings": "Medication choice should balance fracture risk, renal function, adherence, and rare adverse events.；Hip fracture prevention remains the clinically dominant endpoint for orthopaedic relevance.",
        "limitations": "影音轉錄失敗；不阻塞導讀",
        "futureDirections": "補讀全文後確認研究缺口、樣本數、bias 與可外推性。",
        "researchGap": "需要確認哪些 subgroup、outcome 或長期結果仍無一致證據。",
        "clinicalRelevance": "需判斷是否與骨科照護直接相關。",
        "useInReview": "作為背景與證據總結的代表文獻。",
        "themeTags": [
          "clinical-outcomes",
          "mechanism-risk",
          "methods-evidence",
          "teaching-practice"
        ],
        "representativeScore": 9
      },
      {
        "rank": 3,
        "id": "fixture-trauma-image",
        "title": "Orthopaedic Trauma Image Case",
        "year": "2026",
        "journal": "Example Clinical Images",
        "doi": "",
        "pmid": "",
        "studyType": "Case / Image",
        "subspecialty": "Trauma",
        "population": "Orthopaedic trauma patients",
        "interventionExposure": "待人工補讀",
        "comparison": "待人工補讀",
        "outcomes": "Diagnostic teaching point",
        "mainFindings": "A fixture trauma image case requiring manual access.",
        "limitations": "期刊登入 session 可能需重新登入",
        "futureDirections": "補讀全文後確認研究缺口、樣本數、bias 與可外推性。",
        "researchGap": "適合教學或診斷提醒，不適合作為主要研究缺口。",
        "clinicalRelevance": "可能影響骨科臨床決策或教學重點。",
        "useInReview": "可作教學案例，不作主要論證。",
        "themeTags": [
          "methods-evidence",
          "limitations-gap"
        ],
        "representativeScore": 6
      }
    ]
  },
  "selfReview": {
    "schemaVersion": 1,
    "project": "ortho-literature-review",
    "generatedAt": "2026-08-19T10:53:19.609Z",
    "status": "manual_review_required",
    "paperCount": 3,
    "checks": {
      "story": [
        "What is the most important finding?",
        "What story does this result tell?",
        "Which finding belongs in the abstract?",
        "If this were published, what would be the headline result?"
      ],
      "gap": [
        "What research gaps do you see?",
        "What are some alternative explanations?",
        "If you were Reviewer 2, what would you criticize?",
        "What theories could explain this pattern?",
        "What would make this study more interesting?"
      ],
      "figureTable": [
        "How can I improve this figure?",
        "Is this table easy to interpret?",
        "What information is redundant?",
        "How would a reviewer read this figure?"
      ],
      "writing": [
        "Make this paragraph more concise.",
        "Does this argument make sense?",
        "Which part is repetitive?",
        "Is this discussion overinterpreting the results?"
      ]
    }
  },
  "synthesisFiles": [
    "research-projects/ortho-literature-review/synthesis/clinical-outcomes.md"
  ],
  "nodes": [
    {
      "id": "source-papers",
      "title": "來源文獻",
      "mode": "local/manual",
      "status": "ready",
      "description": "status.json / source-papers.json / OpenWiki paper notes",
      "project": "ortho-literature-review"
    },
    {
      "id": "literature-matrix",
      "title": "文獻矩陣",
      "mode": "local",
      "status": "needs_more_papers",
      "description": "研究目的、方法、對象、變項、發現、限制、缺口",
      "project": "ortho-literature-review"
    },
    {
      "id": "theme-tags",
      "title": "主題標籤",
      "mode": "local + AI review",
      "status": "ready",
      "description": "3-5 個反覆概念與每篇文獻歸類",
      "project": "ortho-literature-review"
    },
    {
      "id": "theme-synthesis",
      "title": "主題深入分析",
      "mode": "Claude/manual",
      "status": "draft",
      "description": "共同性、差異性、可能解釋、研究缺口",
      "project": "ortho-literature-review"
    },
    {
      "id": "representatives",
      "title": "代表性文獻",
      "mode": "local + human",
      "status": "ready",
      "description": "依品質、影響力、近期性與臨床重要性排序",
      "project": "ortho-literature-review"
    },
    {
      "id": "review-draft",
      "title": "文獻回顧草稿",
      "mode": "Claude/manual",
      "status": "scaffold",
      "description": "依主題與論點寫，不逐篇介紹作者",
      "project": "ortho-literature-review"
    },
    {
      "id": "self-review",
      "title": "投稿前自審",
      "mode": "human + AI",
      "status": "manual_review_required",
      "description": "核心結論、論文故事、圖表、overinterpretation 檢查",
      "project": "ortho-literature-review"
    },
    {
      "id": "human-pi",
      "title": "Human PI 判斷",
      "mode": "manual",
      "status": "manual_required",
      "description": "研究問題、臨床解釋與投稿前最終決策",
      "project": "ortho-literature-review"
    }
  ],
  "edges": [
    [
      "source-papers",
      "literature-matrix"
    ],
    [
      "literature-matrix",
      "theme-tags"
    ],
    [
      "theme-tags",
      "theme-synthesis"
    ],
    [
      "theme-synthesis",
      "representatives"
    ],
    [
      "representatives",
      "review-draft"
    ],
    [
      "review-draft",
      "self-review"
    ],
    [
      "self-review",
      "human-pi"
    ]
  ],
  "commands": {
    "init": "npm --prefix \".\" run research:init -- ortho-literature-review",
    "matrix": "npm --prefix \".\" run research:matrix -- ortho-literature-review runs/2026-07-25/status.json",
    "themes": "npm --prefix \".\" run research:themes -- ortho-literature-review",
    "synthesize": "npm --prefix \".\" run research:synthesize -- ortho-literature-review --theme clinical-outcomes",
    "representatives": "npm --prefix \".\" run research:representatives -- ortho-literature-review",
    "reviewDraft": "npm --prefix \".\" run research:review-draft -- ortho-literature-review",
    "selfReview": "npm --prefix \".\" run research:self-review -- ortho-literature-review",
    "map": "npm --prefix \".\" run research:map -- ortho-literature-review"
  }
}
